E1 Death’s Reach was the first 4th edition Dungeons and Dragons adventure for the epic tier of play. Released in April 2009, it followed on from the Assault on Nightwyrm Fortress adventure and led into to the second epic tier adventure Kingdom of the Ghouls. For character levels 21-24 the adventure is written by Bruce R. Cordell and Chris Sims. The adventure takes place mostly on the Shadowfell.

Death's Reach is a D&D adventure designed to take characters from 21st to 24th level. In this adventure, players learn the very foundation of reality is threatened by those seeking to usurp the powers of the god of death. To prevent this cosmic coup, players must trace the disruptions into the Shadowfell's timeless core, where all things find their end.

This adventure can be run as a stand-alone adventure or as Part One of a three-part series of adventures (beginning with this one) that spans the epic tier of gameplay.